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导师队伍

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【朱晓静】

朱晓静 副研究员

导师类别：硕士生导师

研究方向：哺乳动物头面部器官发育及新生缺陷的发育及遗传学机制研究

联系电话：0571-28865657

电子邮件：xiao_jingzhu@hotmail.com

通讯地址：浙江省杭州市下沙高教园区学林街16号，310036

个人简历：

1999.09-2003.06 中国药科大学生物制药学院生物工程系工学学士

2003.09-2008.06 浙江大学生命科学学院理学博士

2008.07-2010.06 浙江大学医学院基础医学系博士后

2010.07-2011.09 杭州师范大学生命与环境科学学院助理研究员

2012.09-现在杭州师范大学生命与环境科学学院副研究员

科研项目：

1. 项目名称“Wnt 信号调节蛋白Gpr177 在小鼠上腭发育中的功能研究”；国家青年科学基金项目；项目编号：NO. 31201090，24万。

2. 项目名称“Wnt信号节蛋白Gpr177在小鼠牙齿器官发育中的功能研究”；浙江省自然基金面上项目；项目编号：NO. LY12C12002， 8万。

授权专利：

1. 国家发明专利：一种全长cDNA均一化消减杂交方法（专利号： ZL200710069011.5）戴忠敏，朱晓静，杨卫军。授权公告日：2010.11.10。

2. 国家发明专利：一种无差别扩增双链cDNA及基因组的方法（专利号： ZL 2010 1 0612406.7）朱晓静，赵盼，戴忠敏，张遵义。授权公告日：2012.5.16。

发表SCI论文：

1. X.J. Zhu, P. Zhao, Y Liu, X. Zhang, J. Fu, H.M. Yu, M. Qiu, Y. Chen, W. Hsu, Z. Zhang*,"Intra-epithelial requirement of canonical Wnt signaling for tooth morphogenesis, " J Biol Chem, 288(2013),12080-9.

2. X.J. Zhu, X. Liu, Q. Jin, Y. Cai, Y. Yang and T. Zhou, "The L279P mutation of nuclear distribution gene C (NudC) influences its chaperone activity and lissencephaly protein 1 (LIS1) stability," J Biol Chem, 285 (2010), 29903-10.

3. X.J. Zhu, J.Q. Dai, X. Tan, Y. Zhao and W.J. Yang, "Activation of an AMP-activated protein kinase is involved in post-diapause development of Artemia franciscana encysted embryos," BMC Dev Biol, 9 (2009), 21.

4. X.J. Zhu, C.Z. Feng, Z.M. Dai, R.C. Zhang and W.J. Yang, "AMPK alpha subunit gene characterization in Artemia and expression during development and in response to stress," Stress, 10 (2007), 53-63.

5. X.J. Zhu, Z.M. Dai, J. Liu and W.J. Yang, "Actin gene in prawn, Macrobrachium rosenbergii: characteristics and differential tissue expression during embryonic development," Comp Biochem Physiol B Biochem Mol Biol, 140 (2005), 599-605.

6. Z.M. Dai, X.J. Zhu and W.J. Yang, "Full-length normalization subtractive hybridization: a novel method for generating differentially expressed cDNAs," Mol Biotechnol, 43 (2009), 257-63.

7. J.Q. Dai, X.J. Zhu, F.Q. Liu, J.H. Xiang, H. Nagasawa and W.J. Yang, "Involvement of p90 ribosomal S6 kinase in termination of cell cycle arrest during development of Artemia-encysted embryos," J Biol Chem, 283 (2008), 1705-12.

8. M.R. Wang, X.J. Zhu, J.S. Yang, Z.M. Dai, K. Mahmood, F. Yang and W.J. Yang, "Prawn lipocalin: characteristics and expressional pattern in subepidermal adipose tissue during reproductive molting cycle," Comp Biochem Physiol B Biochem Mol Biol, 147 (2007), 222-9.

9. Z.M. Dai, X.J. Zhu, Q. Chen and W.J. Yang, "PCR-suppression effect: kinetic analysis and application to representative or long-molecule biased PCR-based amplification of complex samples," J Biotechnol, 128 (2007), 435-43.

10. J. Liu, W.J. Yang, X.J. Zhu, N.K. Karouna-Renier and R.K. Rao, "Molecular cloning and expression of two HSP70 genes in the prawn, Macrobrachium rosenbergii," Cell Stress Chaperones, 9 (2004), 313-23.